[1]钟漓 赵志 朱小宝.腹腔镜袖状胃切除术在治疗肥胖症和2型糖尿病中的应用价值[J].中华肥胖与代谢病电子杂志,2017,(01):29-32.[doi:10.3877/cma.j.issn.2095-9605.2017.01.006]
 Zhong Li,Zhao Zhi,Zhu Xiaobao.Application value of laparoscopic sleeve gastrectomy in treating obesity and type 2 diabetes mellitus[J].Chinese Journal of Obesity and Metabolic Disease (Electronic Edition),2017,(01):29-32.[doi:10.3877/cma.j.issn.2095-9605.2017.01.006]
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腹腔镜袖状胃切除术在治疗肥胖症和2型糖尿病中的应用价值()
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《中华肥胖与代谢病电子杂志》[ISSN:2095-9605/CN:11-9362]

卷:
期数:
2017年01期
页码:
29-32
栏目:
临床研究
出版日期:
2017-02-28

文章信息/Info

Title:
Application value of laparoscopic sleeve gastrectomy in treating obesity and type 2 diabetes mellitus
作者:
钟漓 赵志 朱小宝
541000 广西,桂林医学院附属医院胃肠外科
Author(s):
Zhong Li Zhao Zhi Zhu Xiaobao
Department of Gastrointestinal Surgery, Affiliated Hospital of Guilin Medical College, Guangxi Province 541000, China
关键词:
腹腔镜袖状胃切除术 肥胖症 糖尿病2型
Keywords:
Laparoscopic sleeve gastrectomy Obesity Diabetes mellitus type2
DOI:
10.3877/cma.j.issn.2095-9605.2017.01.006
摘要:
目的 探讨腹腔镜袖状胃切除术(LSG)在治疗肥胖症和2型糖尿病中的应用价值。方 法 回顾性分析2011年1月至2013年12月在桂林医学院附属医院胃肠外科接受LSG治疗的24例肥胖 症患者的临床资料。所有患者均签署知情同意书,符合医学伦理学规定。其中男9例,女15例;平均年 龄(28±6)岁。患者行LSG治疗。记录术前和术后多个时间点患者的体质量、体质指数(BMI)、多 余体质量减少百分比、空腹血糖(FPG)、糖化血红蛋白(HbA1c)、甘油三酯(TG)、高密度脂蛋白胆 固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)等指标。手术前后临床指标的比较采用t检验。结 果 术后2年,LSG患者的BMI、FPG、HbA1c、TG、LDL-C分别为(39±11)kg/m 2 、 (6.5±0.7)mmol/L、 (6.0±0.5)%、 (1.8±1.0)mmol/L、 (2.1±0.7)mmol/L,明显低于术前的(50±11)kg/m 2 、 (9.2±0.7)mmol/L、 (7.9±1.8)%、 (2.5±1.0)mmol/L、 (2.9±0.9)mmol/L(t=5.976、4.731、15.457、8.327、3.726,P<0.05);2型 糖尿病的治疗有效率为100%,高脂血症的治愈率为75%。结论 LSG治疗肥胖症和2型糖尿病的短中期 疗效较好,值得在临床上推广使用。
Abstract:
Objective To investigate the clinical application value of laparoscopic sleeve gastrectomy (LSG) in treating obesity and type 2 diabetes mellitus. Methods Clinical data of 24 obese patients undergoing LSG in the Affiliated Hospital of Guilin Medical College from January 2011 to December 2013 were retrospectively studied. The informed consents of all patients were obtained and the local ethical committee approval had been received. Among the 24 patients, 9 were males and 15 were females with an average age of (28±6) years old. All patients received LSG, and their body weight, body mass index (BMI), percentage of excess body weight loss, fasting plasma glucose (FPG), glycosylated hemoglobin A1c (HbA1c), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) were collected before and after operation. Comparisons of these data before and after operation were conducted using t test. Results Two years after operation, BMI, FPG, HbA1c, TG, LDL-C of these patients were (39±11) kg/m 2 , (6.5±0.7) mmol/L, (6.0±0.5)%, (1.8±1.0) mmol/L and (2.1±0.7) mmol/L respectively, which were significantly lower than (50±11) kg/m 2 , (9.2±0.7) mmol/L, (7.9±1.8)%, (2.5±1.0) mmol/L and (2.9±0.9) mmol/L before operation (t=5.976, 4.731, 15.457, 8.327, 3.726, P<0.05); the effective rate of type 2 diabetes mellitus was 100%, and the cure rate of hyperlipemia was 100%. Conclusions LSG has a good short- and mid-term curative effect on obesity and type 2 diabetes mellitus, so it is worthy of clinical promotion and application.

参考文献/References:

[1] Colberg SR, Sigal RJ, Yardley JE, et al. Physical activity/exercise and diabetes: a position statement of the American diabetes association[J]. Diabetes care, 2016, 39(11):2065-2079.
[2] Abbas M, Cumella L, Zhang Y, et al. Outcomes of laparoscopic sleeve gastrectomy and roux-en-Y gastric bypass in patients older than 60[J]. Obes Surg, 2015, 25(12):2251-2256.
[3] Aminian A, Brethauer SA, Andalib A, et al. Can sleeve gastrectomy "Cure" diabetes? Long-term metabolic effects of sleeve gastrectomy in patients with type 2 diabetes[J]. Ann Surg, 2016, 264(4):674-681.
[4] Wang X, Chang XS, Gao L, et al. Effectiveness of laparoscopic sleeve gastrectomy for weight loss and obesity-associated co-morbidities: a 3-year outcome from mainland Chinese patients[J]. Surg Obes Relat Dis, 2016, 12(7):1305-1311.
[5] Chong K, Ikramuddin S, Lee WJ, et al. National differences in remission of type 2 diabetes mellitus after Roux-en-Y gastric bypass surgery-subgroup analysis of 2-year results of the diabetes surgery study comparing taiwanese with Americans with mild obesity (BMI 30-35 kg/m 2 )[J]. Obes Surg, 2016. [Epub ahead of print]
[6] Serrano OK, Zhang Y, Kintzer E, et al. Outcomes of bariatric surgery in the young: a single-institution experience caring for patients under 21 years old[J]. Surg Endosc, 2016, 30(11):5015-5022.
[7] Sevincer GM, Konuk N, Bozkurt S, et al. Food addiction and the outcome of bariatric surgery at 1-year: Prospective observational study[J]. Psychiatry Res, 2016(244):159-164.
[8] Bai RX, Yan WM, Li YG, et al. Application of side-to-side anastomosis of the lesser curvature of stomach and jejunum in gastric bypass[J]. World J Gastroenterol, 2016, 22(37):8398-8405.

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备注/Memo

备注/Memo:

基金项目:广西壮族自治区自筹课题(Z20102404)
通讯作者:钟漓,Email:zhongli0302@163.com
更新日期/Last Update: 2017-02-28